Singles
2012 São Léo Open
Champion	Horacio Zeballos
Runner-up	Paul Capdeville
Score	3–6, 7–5, 7–6(7–2)

Leonardo Mayer was the defending champion but decided not to participate.
Horacio Zeballos defeated Paul Capdeville 3–6, 7–5, 7–6^(7–2) in the final.

Seeds

Draw

Finals

	Semifinals							Final
	8	Paul Capdeville	6	6
		Diego Schwartzman	1	1
								8	Paul Capdeville	6	5	62
								3	Horacio Zeballos	3	7	77
	3	Horacio Zeballos	5	6	6
	2	Blaž Kavčič	7	3	2

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	A Haider-Maurer	6	6
		M Felder	3	2				1	A Haider-Maurer	6	1	61
		Enrico Becuzzi	0	1				Q	T Brkić	1	6	77
	Q	T Brkić	6	6											Q	T Brkić	2	3
	WC	JP Sorgi	7	6											8	P Capdeville	6	6
		H Podlipnik	5	1				WC	JP Sorgi	3	66
		A Collarini	2	3				8	P Capdeville	6	78
	8	P Capdeville	6	6																		8	P Capdeville	6	6
	4	R Dutra da Silva	66	6	6																		D Schwartzman	1	1
	Q	A Satschko	78	0	3			4	R Dutra da Silva	5	7	6
	Q	Wilson Leite	7	6				Q	W Leite	7	5	4
		A Ghem	5	4											4	R Dutra da Silva	2	62
		Leandro Migani	2	1												D Schwartzman	6	77
		P Galdón	6	6					P Galdón	1	1
		D Schwartzman	77	6					D Schwartzman	6	6
	6	J Souza	63	3

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	7	A Veić	6	6
	WC	Gabriel Friedrich	3	1				7	A Veić	3	67
		F de Paula	7	6					F de Paula	6	79
		J Pereira	5	3												F de Paula	1	2
		B Pašanski	6	6											3	H Zeballos	6	6
		A Motti	1	4					B Pašanski	4	77	0
	Q	Diego Matos	2	2				3	H Zeballos	6	65	6
	3	H Zeballos	6	6																		3	H Zeballos	5	6	6
	5	G Elias	6	6																		2	B Kavčič	7	3	2
	WC	Stefano Blatt	1	0				5	G Elias	6	6
		G Andreozzi	2	7	62				A Velotti	1	1
		A Velotti	6	5	77										5	G Elias	4	2
	WC	F Neis	5	3											2	B Kavčič	6	6
		G Clezar	7	6					G Clezar	4	6	3
		J Silva	4	66				2	B Kavčič	6	3	6
	2	B Kavčič	6	78

References

• Main Draw
• Qualifying Draw