380 may refer to:
- 380 (number), the natural number and/or integer
 - Western-calendar years:
 - Products:
- Airbus A380, double-deck, four-engined airliner
 - 380 bulb, 12V dual-brightness (21W/5W, typically automotive) light bulb
 - .380 ACP, a rimless, straight-walled pistol cartridge
 
 - Hung Shui Kiu stop, Hong Kong; station code
 
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