4-Maleylacetoacetic acid

Names
Preferred IUPAC name (2Z)-4,6-Dioxooct-2-enedioic acid
Other names 4-Maleylacetoacetate
Identifiers
CAS Number	5698-52-2 N
3D model (JSmol)	Interactive image
ChEBI	CHEBI:47904 Y
ChEMBL	ChEMBL1743220 N
ChemSpider	4444078 Y
KEGG	C01036 Y
PubChem CID	5280393
UNII	5ET93TW8TE Y
InChI InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1- Y Key: GACSIVHAIFQKTC-UPHRSURJSA-N Y InChI=1/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1- Key: GACSIVHAIFQKTC-UPHRSURJBV
SMILES O=C(/C=C\C(=O)O)CC(=O)CC(=O)O
Properties
Chemical formula	C8H8O6
Molar mass	200.146 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

4-Maleylacetoacetate (4-maleylacetoacetatic acid) is an intermediate in the metabolism of tyrosine. It is converted to fumarylacetoacetate by the enzyme 4-maleylacetoacetate cis-trans-isomerase. Gluthathione coenzymatically helps in conversion to fumarylacetoacetic acid.

See also

• Homogentisate 1,2-dioxygenase