Charles Greene may refer to:
- Charles Ezra Greene (1842–1903), American civil engineer
- Charles Gordon Greene (1804–1886), American journalist
- Charles Greene (athlete) (1945–2022), American athlete
- Charles Sumner Greene (1868–1957), American architect
- Charles Warren Greene (1840–1920), American journalist and author
- Charles Wilson Greene (1866–1947), American professor of physiology and pharmacology
See also
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