Charles Sims may refer to:
- Charles Sims (painter) (1873–1928), British painter
 - Charles Sims (mathematician) (1938–2017), American mathematician
 - Charles Sims (aviator) (1899–1929), British World War I flying ace
 - Charles Sims (American football) (born 1990), American football player
 - Charles Sims (politician), in Toronto municipal elections from 1944 to 1952
 - Charles Edward Sims (1925–1983), State Librarian of Kansas, 1973–1975
 - Charles N. Sims (1835–1908), chancellor of Syracuse University
 - Charles Sims (Surveyor General), Surveyor General of Ceylon, 1858–1865
 
See also
- Charles Simms (disambiguation)
 - Charles Sim, an Australian cricketer
 
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