ICRF 193
Names
IUPAC name
4-[2-(3,5-Dioxo-1-piperazinyl)-1-methylpropyl]piperazine-2,6-dione
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH ICRF+193
  • InChI=1S/C12H18N4O4/c1-7(15-3-9(17)13-10(18)4-15)8(2)16-5-11(19)14-12(20)6-16/h7-8H,3-6H2,1-2H3,(H,13,17,18)(H,14,19,20) checkY
    Key: OBYGAPWKTPDTAS-UHFFFAOYSA-N checkY
  • InChI=1/C12H18N4O4/c1-7(15-3-9(17)13-10(18)4-15)8(2)16-5-11(19)14-12(20)6-16/h7-8H,3-6H2,1-2H3,(H,13,17,18)(H,14,19,20)
    Key: OBYGAPWKTPDTAS-UHFFFAOYAB
  • O=C2NC(=O)CN(C(C(N1CC(=O)NC(=O)C1)C)C)C2
Properties
C12H18N4O4
Molar mass 282.30 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references

ICRF 193 is a topoisomerase inhibitor.[1]

References

  1. ↑ Robinson HM, Bratlie-Thoresen S, Brown R, Gillespie DA (May 2007). "Chk1 is required for G2/M checkpoint response induced by the catalytic topoisomerase II inhibitor ICRF-193". Cell Cycle. 6 (10): 1265–7. doi:10.4161/cc.6.10.4225. PMID 17495539.
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