Iset or ISET may refer to:
- Iset, an Ancient Egyptian name
 - Isis, a goddess in Ancient Egyptian religious beliefs
 - Iset (village), a village in Kachugsky District, Irkutsk Oblast, Russia
 - Iset (river), a river in Russia rising in the Ural Mountains and flowing east into the Tobol River
 - International Solar Electric Technology is a solar power company
 - International School of Economics at Tbilisi State University, a graduate school of economics in Tbilisi
 - International Symposium on Endovascular Therapy - trade conference
 - Inner sphere electron transfer, a mechanism of electron transfer in inorganic chemistry
 - Institut Supérieur des Études Technologiques, or Higher Institute of Technological Studies, a class of universities in Tunisia
 - ISET Test, a diagnostic blood test that detects circulating tumor cells in a blood sample
 
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