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Lyme or LYME may refer to:
- Lyme disease, an infectious disease carried by ticks caused by bacteria of the genus Borrelia
 
Places
United Kingdom
- Lyme, an alternative name of Lyme Handley, a civil parish in Cheshire
- Lyme Park, an estate in Cheshire
 
 - Lyme Regis, a town in Dorset commonly known as Lyme
- Lyme Bay, an area of the English Channel
 
 - Lyme Brook, tributary stream of the River Trent, Staffordshire
 - Forest of Lyme, a historic area of forest covering parts of Cheshire, Derbyshire, and Staffordshire
 
United States
- Lyme, Connecticut, a town in southeastern Connecticut, the namesake of Lyme disease
- Old Lyme, Connecticut, a neighboring town
 - East Lyme, Connecticut, a neighboring town
 
 - Lyme, New Hampshire, a town in western New Hampshire
 - Lyme, New York, a town in New York along the Lake Ontario shoreline
 - Lyme Township, Huron County, Ohio, a small town in northern Ohio
 
Other places
- Lyme Park, Gauteng, a suburb of Johannesburg, South Africa
 
Ships
- English ship Lyme (1654), 52-gun third rate Speaker-class frigate built at Portsmouth, launched in 1654
 - HMS Lyme, any of several vessels of the British Royal Navy
 - RFA Lyme Bay (L3007), a landing ship dock of the British Royal Fleet Auxiliary
 - Lyme-class frigate, class of two 24-gun sixth-rate frigates of the Royal Navy
 
People
- David Lyme (born 1966), also known as Jordi Cubino, a Catalan singer, songwriter, and model
 
Other uses
- LYME (software bundle), a solution stack consisting of Linux, Yaws, Mnesia, and Erlang
 - Lyme Art Association, arts organization established in 1914, with roots going back to 1902
 - Lyme-grass or Leymus arenarius
 
See also
- Ashton-under-Lyme, a market town in Tameside, Greater Manchester, England
 - Newcastle-under-Lyme, a town and borough in Staffordshire, England
 - Lyme and Cybelle, a male and female American folk/pop duo of the mid 1960s
 - New Lyme (disambiguation), several towns in the United States
 - Lime (disambiguation)
 - Flyme (disambiguation)
 - Glyme (disambiguation)
 - Uplyme
 - All pages with titles beginning with Lyme
 - All pages with titles containing Lyme
 
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