The following highways are numbered 180:

Australia

• Pyrenees Highway

Canada

• New Brunswick Route 180
• Prince Edward Island Route 180
• Winnipeg Route 180

Costa Rica

• National Route 180

Ireland

• R180 road (Ireland)

Japan

• Japan National Route 180

Malaysia

• A180 A180 road (Malaysia) (Jalan Ayer Hitam Labu)
• North–South Port Link (Federal Route 180)

Mexico

• Mexican Federal Highway 180
• Mexican Federal Autopista 180D

Russia

• A180 highway (Russia)

United Kingdom

• A180 road (England)
• M180 motorway

United States

• Interstate 180 (disambiguation)
  • Interstate 180 (Illinois)
  • Interstate 180 (Nebraska)
  • Interstate 180 (Pennsylvania)
  • Interstate 180 (Wyoming)
• U.S. Route 180
• Alabama State Route 180
• Arizona State Route 180A
• Arkansas Highway 180
• California State Route 180
• Florida State Road 180 (former)
• Georgia State Route 180
• Hawaii Route 180
• Illinois Route 180
• K-180 (Kansas highway) (former)
• Kentucky Route 180
• Louisiana Route 180
• Maine State Route 180
• Maryland Route 180
• M-180 (Michigan highway) (former)
• Missouri Route 180
• New Jersey Route 180 (former)
• New York State Route 180
• North Carolina Highway 180
• Ohio State Route 180
• Oregon Route 180
• Tennessee State Route 180
• Texas State Highway 180
  • Texas State Highway Spur 180
  • Farm to Market Road 180 (Texas)
• Utah State Route 180
• Virginia State Route 180
• West Virginia Route 180
• Wisconsin Highway 180

Territories

• Puerto Rico Highway 180