Hydrocodone/homatropine
Combination of
HydrocodoneOpioid agonist
HomatropineMuscarinic antagonist
Clinical data
Trade namesTussigon, Hycodan, Hydromet, others
AHFS/Drugs.comMicromedex Detailed Consumer Information
License data
Routes of
administration		By mouth
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
KEGG

Hydrocodone/homatropine, sold under the brand name Tussigon among others, is a fixed-dose combination medication used for the treatment of cough.[1][2] It contains hydrocodone, as the bitartrate, an opioid agonist; and homatropine, as the methylbromide, a muscarinic antagonist.[1][2] It is taken by mouth.[1][2]

Hydrocodone/homatropine was approved for medical use in the United States in 1943.[1][2]

Adverse effects

In the US, the label for hydrocodone/homatropine contains a black box warning about addiction, abuse, and misuse.[1][2]

References

  1. 1 2 3 4 5 6 "Hycodan- hydrocodone bitartrate and homatropine methylbromide tablet; Hycodan- hydrocodone bitartrate and homatropine methylbromide solution". DailyMed. 29 December 2021. Retrieved 23 December 2023.
  2. 1 2 3 4 5 6 "Hydromet- hydrocodone bitartrate and homatropine methylbromide solution". DailyMed. 30 September 2022. Retrieved 23 December 2023.


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